RNA-seq analysis evaluating effects of Cdk7 inhibitor THZ1 on responses of NRVM to adrenergic receptor agonist PE Overall design: NRVM mRNA profiles from four groups: 1. Vehicle; 2. PE (100 μM); 3. PE
The zebrafish is rapidly emerging as a promising alternative in vivo model for the detection of drug-induced cardiovascular effects. Despite its increasing popularity, the ability of this model to inf
We have shown that both insulin and resveratrol (RSV) decrease neointimal hyperplasia in chow-fed rodents via mechanisms that are in part overlapping and involve the activation of endothelial nitric o
All the values are expressed as mean ± S.E. Heart weight divided by body weight (HW/BW), lung weight divided by body weight (LW/BW) and kidney weight divided by body weight (KW/BW) were also calculate