RENIN IN COMPLEXED WITH 4-methoxy-3-(3-methoxypropoxy)-N-{[(3S,4S)-4-{[(4-methylphenyl)sulfonyl]amino}pyrrolidin-3-yl]methyl}-N-(propan-2-yl)benzamide INHIBITOR

Protein Data Bank Japan2024-11-06 更新2026-03-21 收录

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https://pdbj.org/mine/summary/4ryc

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RENIN IN COMPLEXED WITH 4-methoxy-3-(3-methoxypropoxy)-N-{[(3S,4S)-4-{[(4-methylphenyl)sulfonyl]amino}pyrrolidin-3-yl]methyl}-N-(propan-2-yl)benzamide INHIBITOR Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 4-methoxy-3-(3-methoxypropoxy)-N-{[(3S,4S)-4-{[(4-methylphenyl)sulfonyl]amino}pyrrolidin-3-yl]methyl}-N-(propan-2-yl)benzamide, DIMETHYL SULFOXIDE, ... Authors: Ostermann, N. Deposit date: 2014-12-15 Release date: 2015-03-25 Last modified: 2024-11-06 Method: X-RAY DIFFRACTION (2.45 Å) Cite: trans-(3S,4S)-Disubstituted pyrrolidines as inhibitors of the human aspartyl protease renin. Part I: Prime site exploration using an amino linker. Bioorg.Med.Chem.Lett., 25, 2015

创建时间：

2014-12-15