five

Hepatitis C virus polymerase NS5B (BK) with amide bioisostere thumb site inhibitor

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Protein Data Bank Japan2024-02-21 更新2026-03-21 收录
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https://pdbj.org/mine/summary/3mf5
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Hepatitis C virus polymerase NS5B (BK) with amide bioisostere thumb site inhibitor Descriptor: 3-[2-(trans-4-methylcyclohexyl)phenyl]-5-phenylthiophene-2-carboxylic acid, GLYCEROL, RNA-directed RNA polymerase Authors: Harris, S.F, Tavares, G, Ghate, M. Deposit date: 2010-04-01 Release date: 2010-07-28 Last modified: 2024-02-21 Method: X-RAY DIFFRACTION (2 Å) Cite: Cyclic amide bioisosterism: Strategic application to the design and synthesis of HCV NS5B polymerase inhibitors. Bioorg.Med.Chem.Lett., 20, 2010
创建时间:
2010-04-01
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