Classification performance with three benchmark datasets.

a Total of 249,500 domain pairs selected randomly from SCOPe_NR10.b Total of 249,500 domain pairs selected randomly from SCOPe_FAMILY.c Total of 99,792 protein pairs selected randomly from PDB30.d–f SCOPe classification.g Area under the ROC curve.h Area under the PRC.i Number of alignments calculated from the alignment program.The best performances among the four structure alignment methods are indicated in bold.AUC, area under the ROC curve; AUPRC, area under the PRC; CAB-align, contact area-based alignment; PDB, protein data bank; PRC, precision-recall curve; ROC, receiver-operating characteristic.Classification performance with three benchmark datasets.