Human thymidylate kinase complexed with AZTMP and APPNP

Human thymidylate kinase complexed with AZTMP and APPNP Descriptor: 3'-AZIDO-3'-DEOXYTHYMIDINE-5'-MONOPHOSPHATE, ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, ... Authors: Ostermann, N, Lavie, A, Padiyar, S, Brundiers, R, Veit, T, Reintein, J, Goody, R.S, Konrad, M, Schlichting, I. Deposit date: 2000-10-10 Release date: 2001-10-05 Last modified: 2024-05-08 Method: X-RAY DIFFRACTION (1.7 Å) Cite: Potentiating Azt Activation: Structures of Wildtype and Mutant Human Thymidylate Kinase Suggest Reasons for the Mutants' Improved Kinetics with the HIV Prodrug Metabolite Aztmp J.Mol.Biol., 304, 2000