Cinchona pubescens Transcriptome
收藏NIAID Data Ecosystem2026-03-12 收录
下载链接：
http://datadryad.org/dataset/doi%253A10.5061%252Fdryad.z34tmpgcc
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资源简介：
The enzymatic basis for quinine 1 biosynthesis was investigated. Transcriptomic data from the producing plant Cinchona pubescens led to the discovery of three enzymes involved in early and late steps of the pathway. A medium-chain alcohol dehydrogenase (CpDCS) and an esterase (CpDCE) yielded the biosynthetic intermediate dihydrocorynantheal 2 from strictosidine aglycone 3. Additionally, the discovery of an O-methyltransferase specific for 6´-hydroxycinchoninone 4 suggested the final steps order to be cinchoninone 16/17 hydroxylation, methylation and keto-reduction.
Methods
This transcriptomic dataset was acquired from Cinchona pubescens. Illumina data were acquired, assembled and annotated by BGI-seq.
创建时间：
2021-02-23
