Structure of the STLV intasome:B56 complex bound to the strand-transfer inhibitor XZ450
收藏Protein Data Bank Japan2024-07-17 更新2026-04-19 收录
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Structure of the STLV intasome:B56 complex bound to the strand-transfer inhibitor XZ450 Descriptor: 4-azanyl-~{N}-[[2,4-bis(fluoranyl)phenyl]methyl]-6-[3-(dimethylamino)-3-oxidanylidene-propyl]-1-oxidanyl-2-oxidanylidene-1,8-naphthyridine-3-carboxamide, DNA (5'-D(*AP*CP*TP*GP*TP*GP*TP*TP*TP*GP*GP*CP*GP*CP*TP*TP*CP*TP*CP*TP*C)-3'), DNA (5'-D(*GP*AP*GP*AP*GP*AP*AP*GP*CP*GP*CP*CP*AP*AP*AP*CP*AP*CP*A)-3'), ... Authors: Barski, M.S, Ballandras-Colas, A, Cronin, N.B, Pye, V.E, Cherepanov, P, Maertens, G.N. Deposit date: 2021-06-11 Release date: 2021-08-18 Last modified: 2024-07-17 Method: ELECTRON MICROSCOPY (3 Å) Cite: Structural basis for the inhibition of HTLV-1 integration inferred from cryo-EM deltaretroviral intasome structures. Nat Commun, 12, 2021
创建时间:
2021-06-11



