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Prion infected ScN2a and GT1
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2010-06-09
相关数据集
In vivo base editing extends lifespan of a humanized mouse model of prion disease
Prion disease is a fatal neurodegenerative disease caused by the misfolding of prion protein (PrP) encoded by the PRNP gene. While there is currently no cure for the disease, depleting PrP in the brai
NIAID Data Ecosystem80
Microarray data CEL files supporting the paper "Microarray profiling emphasizes transcriptomic differences between hippocampal in vivo tissue and in vitro cultures"
Affymetrix microarray processing produced 16 (4 WT cell, 4 101LL cell, 4 WT tissue, 4 101LL tissue) probe cell intensity data (CEL) files. Primary hippocampal cell cultures are routinely used as an ex
DataCite Commons2023-04-27 更新60
Susceptibility of transgenic and C57BL/10 mice to four strains of scrapie.
a = For strain RML, two different stocks, RML-06 and RML-81 were studied.b = Incubation period is average days post-inoculation to disease +/− standard deviation.c = not applicable (mice did not devel
Figshare2015-12-02 更新20
De Novo Generation of Infectious Prions In Vitro Produces a New Disease Phenotype
Prions are the proteinaceous infectious agents responsible for Transmissible Spongiform Encephalopathies. Compelling evidence supports the hypothesis that prions are composed exclusively of a misfolde
NIAID Data Ecosystem70
Single-cell transcriptomics of mammalian prion diseases identifies dynamic gene signatures shared between species
This SuperSeries is composed of the SubSeries listed below. Refer to individual Series
NIAID Data Ecosystem40
