Transcriptomic comparison of the vitamin A ester retinyl propionate and retinol in human keratinocytes. Transcriptomic comparison of the vitamin A ester retinyl propionate and retinol in human keratinocytes

Retinoids are potent skin care actives used to treat a number of common clinical and cosmetic skin conditions, including skin aging. Here, we compare the effects of retinyl proprionate and retinol on gene expression in immortalized human keratinocytes. Overall design: Immortalized human keratinocytes (hTERT) were treated with 100nM retinyl proprionate or 100nM retinol for 24 hr and subjected to microarray profiling on the GeneTitan U219 array platform.