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Demystifying excess immune response in COVID-19 to reposi-tion an orphan drug for down-regulation of NF-κB: A systematic review

Mendeley Data2021-01-14 更新2026-04-09 收录

COVID-19凝血与免疫病理机制

药物重定位

数据链接：

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资源简介：

Screening, Risk of Bias Assessment, and Data Extraction for the Systematic Review.

应用场景：

创建时间：

2021-01-14

药物重定位

病毒-宿主相互作用

Sheet (a) summarizes the overlap between the top-scoring proteins associated with the drugs and the top-scoring proteins associated with SARS-CoV-2 infection sets. Sheet (b) contains figures that illu

NIAID Data Ecosystem90

Global Transcriptomic analysis of PBMC derived from COVID-19 acute-severe patients and convalescents

传染病免疫转录组学

COVID-19凝血与免疫病理机制

The majority of patients with COVID-19 have a self-limiting upper respiratory tract infection mostly represented by asymptomatic or mild, however a small but relevant proportion of patients develops a

NIAID Data Ecosystem60

Supplementary Table 1 from Computational Repositioning and Preclinical Validation of Pentamidine for Renal Cell Cancer

药物重定位

癌细胞基因表达

XLSX file - 79KB, Genes regulated by pentamidine in 786-O cells after 6h incubation.

NIAID Data Ecosystem50

An Integrated Data Driven Approach to Drug Repositioning Using Gene-Disease Associations

药物重定位

疾病关联分析

Drug development is both increasing in cost whilst decreasing in productivity. There is a general acceptance that the current paradigm of R&D needs to change. One alternative approach is drug repositi

NIAID Data Ecosystem80

Glucocorticoid promotes metastasis of colorectal cancer via co-regulation of glucocorticoid receptor and TET2 (RNA-Seq). Glucocorticoid promotes metastasis of colorectal cancer via co-regulation of glucocorticoid receptor and TET2 (RNA-Seq)

结直肠癌转移机制

药物重定位

Background Glucocorticoids (GCs), commonly used for anti-inflammatory and cancer treatments, have been linked to the promotion of cancer metastasis. Yet, the molecular mechanisms behind this potential

NIAID Data Ecosystem50

Demystifying excess immune response in COVID-19 to reposi-tion an orphan drug for down-regulation of NF-κB: A systematic review

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