Prediction accuracies of NetNES, Wregex, NESsential, NESmapper, and consensus-based NES predictions using artificial NES test data.

Prediction accuracies of the indicated methods and tools were determined with the artificial NES sets, as in Table 1.aTraditional NES consensus sequence, Φ–X2,3–Φ–X2,3–Φ–X–Φ.bClass 1a, 1b, 1c, 1d, 2, and 3 NES consensus sequences, not allowing A, C, T, or W at positions Φ3 and Φ4 (see Introduction for detail).cPrediction with recommended PSSM configuration.dPrediction with relaxed PSSM configuration.eNESs with the probability values of ≥0.1 selected.fNESs with the probability values of ≥0.5 selected.gPrediction with unoptimized NES profiles, NESs with a score of ≥2 were selected.hPrediction with optimized NES profiles. NESs with a score of ≥2 were selected.Prediction accuracies of NetNES, Wregex, NESsential, NESmapper, and consensus-based NES predictions using artificial NES test data.