The Anaphase Promoting Complex or Cyclosome (APC/C) functions during mitosis to promote sister chromatid separation and mitotic exit through the degradation of mitotic cyclins and securin. This comple

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Additional file 12 of TRIM25 promotes Capicua degradation independently of ERK in the absence of ATXN1L

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蛋白质降解

Additional file 12: Table S5 TRIM25-CIC-ATXN1L gene set enrichment analysis. A) Gene set enrichment analysis of upregulated discordant DE genes shared between TRIM25 vs CIC and TRIM25 vs ATXN1L. B) Ge

Figshare2020-10-29 更新50

Mapping the Degradable Kinome: A Resource for Expedited Degrader Development

蛋白质降解

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Targeted protein degradation refers to the use of small molecule inducers of ubiquitin-dependent degradation of proteins and enables the development of drugs to previously inaccessible targets. Degra

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North America Protein Degradation Market

蛋白质降解

生物制药投资

The North America Protein Degradation report provides a detailed analysis of emerging investment pockets, highlighting current and future market trends. It offers strategic insights into capital flows

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TPC2016-00768-LSBR1_Supplemental_Data_Set_4

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