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Crystal structure of MDM2 with Brigimadlin

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Protein Data Bank Japan2024-12-11 更新2026-04-19 收录
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Crystal structure of MDM2 with Brigimadlin Descriptor: Brigimadlin, E3 ubiquitin-protein ligase Mdm2 Authors: Bader, G, Wolkerstorfer, B. Deposit date: 2023-07-20 Release date: 2024-10-02 Last modified: 2024-12-11 Method: X-RAY DIFFRACTION (1.461 Å) Cite: Discovery and Characterization of Brigimadlin, a Novel and Highly Potent MDM2-p53 Antagonist Suitable for Intermittent Dose Schedules. Mol.Cancer Ther., 23, 2024

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2023-07-20
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