Crystal Structure of human RORgamma (C455E) LBD in complex with compound XY039

Crystal Structure of human RORgamma (C455E) LBD in complex with compound XY039 Descriptor: 2,4-difluoro-N-(1-((4-(trifluoromethyl)benzyl)sulfonyl)-1,2,3,4-tetrahydroquinolin-7-yl)benzenesulfonamide, ETHANOL, GLYCEROL, ... Authors: Wu, X, Li, C, Zhang, Y, Xu, Y. Deposit date: 2022-05-07 Release date: 2023-05-31 Last modified: 2024-06-12 Method: X-RAY DIFFRACTION (2.57 Å) Cite: Discovery and pharmacological characterization of 1,2,3,4-tetrahydroquinoline derivatives as ROR gamma inverse agonists against prostate cancer. Acta Pharmacol.Sin., 2024