Crystal structure of Bcl2 in complex with S-9c
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Crystal structure of Bcl2 in complex with S-9c Descriptor: 4-[4-[(2~{S})-2-(2-chlorophenyl)pyrrolidin-1-yl]phenyl]-~{N}-[3-nitro-4-(oxan-4-ylmethylamino)phenyl]sulfonyl-2-(1~{H}-pyrrolo[2,3-b]pyridin-5-yloxy)benzamide, Apoptosis regulator Bcl-2 Authors: Liu, J, Xu, M, Feng, Y, Liu, Y. Deposit date: 2022-12-21 Release date: 2024-05-15 Last modified: 2024-06-05 Method: X-RAY DIFFRACTION (1.6 Å) Cite: Discovery of the Clinical Candidate Sonrotoclax (BGB-11417), a Highly Potent and Selective Inhibitor for Both WT and G101V Mutant Bcl-2. J.Med.Chem., 67, 2024
创建时间：
2022-12-21
