Crystal structure of an MKP5 mutant, Y435W, in complex with an allosteric inhibitor
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Crystal structure of an MKP5 mutant, Y435W, in complex with an allosteric inhibitor Descriptor: 3,3-dimethyl-1-{[9-(methylsulfanyl)-5,6-dihydrothieno[3,4-h]quinazolin-2-yl]sulfanyl}butan-2-one, Dual specificity protein phosphatase 10 Authors: Manjula, R, Bennett, A.M, Lolis, E. Deposit date: 2024-05-16 Release date: 2025-05-28 Last modified: 2025-08-13 Method: X-RAY DIFFRACTION (2.9 Å) Cite: Dynamic and structural insights into allosteric regulation on MKP5 a dual-specificity phosphatase. Nat Commun, 16, 2025
创建时间：
2024-05-16
