Interaction between a high HR-HPV load and alcohol consumption on the risk of 1-year HR-HPV persistence.

†N w/wo persistence, the number of subjects with/without persistence; OR, odds ratio.1)HPV load was classified as low (2)Multivariate logistic regression analysis was performed with adjustment for age as a continuous variable and for menopausal status, oral contraceptive use, smoking status, and number of children as categorical variables. Risk estimates were calculated with no alcohol consumption, alcohol consumption for 3), 4)The relative excess risk due to interaction (RERI) and synergy index (S) were calculated as described by Rothman et al. RERI>0 and S>1.0 indicate a synergistic effect between HR-HPV load and alcohol consumption behaviors.