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Transciptome profiling of RNaseIII null cells reconstituted with Drosha

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NIAID Data Ecosystem2026-05-17 收录
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To assess the impact of Drosha reconstitution on the overall transcriptome of RNaseIII null cells. Overall design: We utilized CRISPR techology to engineer an RNaseIII null cell line using the NoDice 293T (PMID: 24757167) as the parental cell line. mRNA profiles of RNaseIII null cells were transfected with GFP plus empty plasmid or GFP-Drosha for 3 days.

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2017-09-28
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