Single-cell RNAsequencing of the ventral rhombomere 1 of the developing mouse [INDROPS]

Sequencing of the mouse ventral rhombomere 1 tissues and cells to characterize the Tal1-dependent and -independent neuronal precursor groups. The data allowed to describe the cell types in the R1 brain region, and map gene expression dynamics during bifurcation of the GABAergic and glutamatergic lineages. Our results provide a framework for understanding the development of cellular diversity in the tegmental nuclei. Unlabelled single cells were dissociated from R1 brain region and collected using in-house InDrops single-cell collection setup.