Crystal structure of CRAF/MEK1 complex with PLX4720 and CH5126766
收藏Protein Data Bank Japan2025-11-19 更新2026-04-19 收录
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Crystal structure of CRAF/MEK1 complex with PLX4720 and CH5126766 Descriptor: Dual specificity mitogen-activated protein kinase kinase 1, N-(3-fluoro-4-{[4-methyl-2-oxo-7-(pyrimidin-2-yloxy)-2H-chromen-3-yl]methyl}pyridin-2-yl)-N'-methylsulfuric diamide, N-{3-[(5-chloro-1H-pyrrolo[2,3-b]pyridin-3-yl)carbonyl]-2,4-difluorophenyl}propane-1-sulfonamide, ... Authors: Jang, D.M, Eck, M.J. Deposit date: 2025-04-03 Release date: 2025-10-15 Last modified: 2025-11-19 Method: X-RAY DIFFRACTION (2.91 Å) Cite: Characterization and inhibitor sensitivity of ARAF, BRAF, and CRAF kinases. J.Biol.Chem., 301, 2025
创建时间：
2025-04-03
