Identification of ADAR1 associated proteins

Name: Identification of ADAR1 associated proteins
Creator: Tianjin Medical University
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Identification of ADAR1 associated proteins

提供机构：

Tianjin Medical University

创建时间：

2022-11-15

Identification of ADAR1 associated proteins

To understand how ADAR1 controls genome stability, affinity purification and mass spectrometry were employed to identify the interactomes of ADAR1 with cellular extracts from HeLa cells stably express

国家人口健康科学数据中心00

Identification of ADAR1 adenosine deaminase dependency in a subset of cancer cells. Identification of ADAR1 adenosine deaminase dependency in a subset of cancer cells

Using RNA-seq to identify gene expression changes after genetic deletion of ADAR Overall design: RNA-seq of A549, HCC366, NCI-H1650, and NCI-H196 cells after CRISPR-Cas9-mediated deletion of ADAR as c

NIAID Data Ecosystem40

Identification of double-stranded RNAs modulated by ADAR1

Endogenous double-stranded RNA (dsRNA) triggers pro-inflammatory signaling and has been shown to accumulate in Alzheimer’s disease (AD), but the origins of this dsRNA are incompletely understood. Tran

NIAID Data Ecosystem00

The effect of ADAR1 depletion on mitochondrial proteins

In this study, we found that ADAR1 reduces the levels of double-stranded RNAs (dsRNAs) derived from both nuclear and mitochondrial transcripts. To elucidate how ADAR1 controls mitochondrial dsRNA (mt-

NIAID Data Ecosystem10

Identification of double-stranded RNAs modulated by ADAR1

Endogenous double-stranded RNA (dsRNA) triggers pro-inflammatory signaling and has been shown to accumulate in Alzheimer's disease (AD), but the origins of this dsRNA are incompletely understood. Tran

NIAID Data Ecosystem00