Transcriptional Profile of SCRG Highlights a Progenitor Cell Phenotype.

Ontological categories represented by the SCRG gene set reveal gene groups that are important in NSC regulation. The groups identified include pathways important for cell adhesion and migration, differentiation, proliferation, many signaling molecules and transcription factors. The PPAR signaling pathway is significantly represented (p = 0.036) within the SCRG gene list (genes marked by single asterisks). Percents indicate the number of genes in the ontology grouping, compared with the total number of genes. Genes marked with double asterisks were identified by data mining the literature and databases for NSC genes, and performing additional analysis of expression within RG.