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Impact of Aging on CD146+ Mesenchymal Stromal Cells-Mediated Regulation of Bone Marrow CD34⁺ Hematopoietic Stem/Progenitor Cell Mobilization

ChEBI2026-04-29 更新2026-07-12 收录

造血干细胞动员

衰老细胞生物学

数据链接：

https://www.ebi.ac.uk/biostudies/ArrayExpress/studies/E-MTAB-16622 数据链接链接失效反馈

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Impact of Aging on CD146+ Mesenchymal Stromal Cells-Mediated Regulation of Bone Marrow CD34⁺ Hematopoietic Stem/Progenitor Cell Mobilization

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创建时间：

2026-04-29

造血干细胞动员

多发性骨髓瘤

Introduction: In patients with a clinical indication for autologous hematopoietic stem cell transplantation (ASCT) sufficient mobilization of CD34+ precursor cells into peripheral blood is essential t

DataCite Commons2023-10-24 更新110

The lysosomal proteome of senescent cells contributes to the senescence-associated secretome

衰老细胞生物学

溶酶体蛋白质组学

Senescent cells accumulate in tissues over time, favoring the onset and progression of multiple age-related diseases. The senescence-associated secretory phenotype (SASP) is considered the main patho

NIAID Data Ecosystem80

Molecular phenotype of G-CSF- or pegylated G-CSF-mobilized CD34+ cells. Homo sapiens

造血干细胞动员

CD34+细胞分子表型

Peripheral blood stem and progenitor cells (PBSC) are widely used for autologous and allogeneic hematopoietic stem cell transplantation. PBSC can be mobilized into the peripheral blood using cytokines

NIAID Data Ecosystem50

G-CSF + plerixafor versus G-CSF alone mobilized hematopoietic stem cells in patients with multiple myeloma and lymphoma: a systematic review and meta-analysis

造血干细胞动员

治疗效果

The combination of granulocyte-colony stimulating factor (G-CSF) and plerixafor is one of the approaches for hematopoietic stem cell mobilization in patients with multiple myeloma (MM), non-Hodgkin’s

DataCite Commons2024-12-03 更新90

Nociceptive nerves regulate haematopoietic stem cell mobilization. Nociceptive nerves regulate haematopoietic stem cell mobilization

造血干细胞动员

神经免疫调控

Nociceptive neuropeptide CGRP acts directly on HSCs via the its receptor RAMP1/CALCRL, to promote egress by activating Gαs/Adenylyl cyclase/cAMP pathway. Overall design: mRNA profiles of sorted bone m

NIAID Data Ecosystem70

Impact of Aging on CD146+ Mesenchymal Stromal Cells-Mediated Regulation of Bone Marrow CD34⁺ Hematopoietic Stem/Progenitor Cell Mobilization

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