Solution structures of three immunologically important proteins IgA, C3 and IgG

Abnormally glycosylated IgA leads to IgA nephropathy, the most common cause of renal failure. IgG antibody represents one-third of new drugs currently in development, and its...异常糖基化的免疫球蛋白A（IgA）可诱发IgA肾病（IgA nephropathy），而该肾病是引发肾功能衰竭的最常见病因。免疫球蛋白G（IgG）抗体占目前在研新药的三分之一，且其……