Contractile actomyosin bundles induced by mDia1/3 regulates adherens junction and ectoplasmic specialized junction in Sertoli cells critical for spermatogenesis and male fertility
Human adult spermatogenesis involves a balance of spermatogonial stem cell self renewal and differentiation, alongside complex germline-niche interactions. To better understand, we performed single ce
Sertoli cells, which are the only somatic cells in the seminiferous tubules, facilitate the maintenance of testicular immune privilege through the formation of the blood-testis barrier (BTB) and the e
BackgroundThe RNase III endonuclease Dicer is an important regulator of gene expression that processes microRNAs (miRNAs) and small interfering RNAs (siRNAs). The best-characterized function of miRNAs
Many young adults are in a state of stress due to social and psychological pressures, which may result in male reproductive dysfunction. To provide new insight into this phenomenon, we investigated th
Additional file 7: Table 2. Direct and indirect gene targets of the proteins studied. Direct gene targets are defined as the genes that have a significant peak of a given protein within 1Â kb of their
