CD4∶CD8 T cell ratio and extracellular MHC class I and II expression in spleens of congenic and recombinant strains.

aRT1 haplotype designations are based on genotyping data (see Methods); bStrains were compared in separate experiments to DA littermate controls. The mean fluorescent intensity was then normalized to the expression of DA, which was given an arbitrary value of 100. cMHC-I (class Ia and Ib; OX18) extracellular expression on WBCs. dMHC class II expression on B cells. Significant differences compared to DA: eP<0.001; fP<0.01; gP<0.05. WT, wildtype; PS, parental strain; RCS, recombinant congenic strain. Shown are mean values ±SD.