Blood plasma lipidomics peak area data from 67 children with increased risk of type 1 diabetes and variable number of autoantibodies generated by targeted mass spectrometry

This dataset consists of a single Excel xlsx file containing peak area data for 128 lipid species detected by mass spectrometry from 67 children with increased risk of type 1 diabetes and different number of autoantibodies. Individuals studied herein are participants in the DiabetesPrediction in Skåne Study, a prospective population-based study, following children from birth with the aim to investigate genetic and environmental factors that may contribute to the development of T1D. All participants were 10-15 years of age at the time of sampling and were healthy (no diabetes) with or without autoantibodies. Lipid extracts were analyzed using an ultra-high-performance liquid chromatography quadrupole time-of-flight mass spectrometer (UHPLC-Q-TOF-MS) operated in the positive ion mode. The column was an Acquity UPLC™ BEH C18 2.1×100 mm with 1.7 µm particles from Waters (Milford, CT, USA).This dataset contains raw peak area data for 128 lipid species across 11 classes. These classes and their abbreviations as used in the dataset are as follows:* cholesteryl ester (CE),* ceramide (Cer),* lysophosphatidylcholine (LPC),* phosphatidylcholine (PC),* alkylphosphatidylcholine (PC(O)),* alkenylphosphatidylcholine (plasmalogen, PC(P)),* phosphatidylethanolamine (PE),* alkylphosphatidylethanolamine (PE(O)),* phosphatidylethanolamine plasmalogen (PE(P)),* phosphatidylinositol (PI),* sphingomyelin (SM),* triacylglycerol (TG),Further analysis and explanation of these data are presented in the accompanying manuscript.