TCMSP

TCMSP is a unique systems pharmacology platform of Chinese herbal medicines that captures the relationships between drugs, targets and diseases. The database includes chemicals, targets and drug-target networks, and associated drug-target-disease networks, as well as pharmacokinetic properties for natural compounds involving oral bioavailability, drug-likeness,intestinal epithelial permeability, blood-brain-barrier, aqueous solubility and etc. This breakthrough has sparked a new interest in the search of candidate drugs in various types of traditional Chinese herbs.TCMSP（中药系统药理学数据库与分析平台）是一款独具特色的中草药系统药理学研究平台，能够系统阐释药物、靶点与疾病三者间的关联关系。该数据库涵盖化学物质、靶点及药物-靶点网络，同时包含关联的药物-靶点-疾病网络，此外还收录了天然化合物的多项药代动力学特性，包括口服生物利用度、类药性、肠上皮通透性、血脑屏障穿透性、水溶性等。这一突破性成果为各类中草药的候选药物研发领域催生了全新的研究热潮。

搜集汇总

背景与挑战

背景概述

TCMSP是一个中药系统药理学平台，提供药物、靶点与疾病关系的网络数据，以及天然化合物的药代动力学特性，适用于中药候选药物的研究。