Fungal allergic sensitisation and the gut mycobiome in preschool aged children

Fungal exposure is associated with the risk of allergen sensitisation, and this is thought to be partly influenced by microbiota. While many studies have reported associations between gut microbiota and allergen sensitisation, fewer studies have specifically examined the relationship between gut mycobiome and allergen sensitisation. This study sought to characterise the gut mycobiome of 116 Zimbabwean pre-school aged children (≤5 years old). The characterised gut mycobiome was related to fungal sensitisation assessed by skin prick tests (SPTs) and fungal seroreactivity determined by enzyme-linked immunosorbent assay (ELISA). The raw data and the demographic data are presented here.