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Discovery of a Drug Candidate for GLIS3-Associated Diabetes

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NIAID Data Ecosystem2026-03-11 收录
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https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE114051
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Through development and use of a minimal component protocol for derivation of late stage pancreatic progenitors and beta-like cells, we compared WT and GLIS3-/- pancreatic cells at different stages and discovered that GLIS3-/- cells show an ectopic activation of TGF-beta signaling. Comparison of WT and GLIS3-/- cells at various stages of human pancreatic differentiation
创建时间:
2019-06-17
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