Seizure-induced immediate early gene expression with, vs. without, isoflurane anesthesia

A single electroconvulsive seizure (ECS), versus sham, was administered to anesthetized and non-anesthetized WT male mice. One hour after ECS, mice were sacrificed and perfused. Sectioned brain tissue was immunofluorescently labeled with an antibody against the IEG Arc. Complete methods are found in associated Data in Brief article (Data on serial electroconvulsive seizure in mice, effects of anesthesia and correlation between age and neurogenesis) and original associated article: Meyers, K.T., et al., Serial electroconvulsive Seizure alters dendritic complexity and promotes cellular proliferation in the mouse dentate gyrus; a role for Egr3. Brain Stimul, 2023. 16(3): p. 889-900. https://doi.org/10.1016/j.brs.2023.04.022