Guidance Document on the Diagnosis of Endocrine‑related Histopathology in Fish Gonads

Organisation for Economic Co-operation and Development2026-03-28 收录

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Exposure of fathead minnow (Pimephales promelas), Japanese medaka (Oryzias latipes) and zebrafish (Danio rerio) to endocrine disrupting chemicals may result in histopathological alterations of gonadal structure and microarchitecture. The diagnosis of such histopathological changes may, therefore, assist in the detection of endocrine disrupting...