Structure of Phosphoinositide 3-kinase gamma (PI3K) bound to the potent inhibitor PIKin2
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Structure of Phosphoinositide 3-kinase gamma (PI3K) bound to the potent inhibitor PIKin2 Descriptor: Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform, SULFATE ION, [1-{4-[6-amino-4-(trifluoromethyl)pyridin-3-yl]-6-(morpholin-4-yl)pyrimidin-2-yl}-3-(chloromethyl)azetidin-3-yl]methanol Authors: Burke, J.E, Inglis, A.J, Williams, R.L. Deposit date: 2016-04-20 Release date: 2017-03-15 Last modified: 2024-01-10 Method: X-RAY DIFFRACTION (2.51 Å) Cite: Deconvolution of Buparlisib's mechanism of action defines specific PI3K and tubulin inhibitors for therapeutic intervention. Nat Commun, 8, 2017
创建时间：
2016-04-20
