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Dominant protection from HLA-linked autoimmunity by antigen-specific regulatory T cells.

Name: Dominant protection from HLA-linked autoimmunity by antigen-specific regulatory T cells.
Creator: IEDB
Published: 2017-01-01T00:00:00+08:00

ImmuneData2026-05-21 收录

HLA自身免疫

T细胞表位

数据链接：

https://immunedata.org/display-item.php?repository=0009&id=AWPT8Lzth18v6WY6QS71&query=%20 数据链接链接失效反馈

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资源简介：

The epitope was eluted from HLA-DR from a B cell line expressing HLA-DR1.

应用场景：

提供机构：

IEDB

创建时间：

2017-01-01

免疫肽组学

HLA配体鉴定

The HLA-I-eluted immunopeptidome of the GR lymphoblastoid cell line (GR-LCL) was analyzed by a two-dimensional (2D) peptide prefractionation strategy followed by a hybrid peptide fragmentation method

ImmuneData50

Loss in CD4 T-cell responses to multiple epitopes in influenza due to expression of one additional MHC class II molecule in the host.

T细胞免疫应答

MHC限制性

The epitope sequence was cited in Nayak et al. Viral Immunol. 2010 Apr;23(2):169-80 [PMID:20373997]. Similar results were seen for (B10 x B10.S) F1 mice (H-2bxs). Also, little apparent difference was

ImmuneData30

Selective pre-priming of HA-specific CD4 T cells restores immunological reactivity to HA on heterosubtypic influenza infection.

免疫应答

CD4T细胞反应

CD4 T cell responses directed against the epitope were greatly diminished in the spleen at 8 days following secondary infection compared to the responses following a primary infection.

ImmuneData30

Assessment of seasonal influenza A virus-specific CD4 T-cell responses to 2009 pandemic H1N1 swine-origin influenza A virus.

流感病毒免疫

疫苗效果评估

The epitope specific CD4+ T cell line proliferated in response to the Fluzone vaccine formulation from 2004-2005.

ImmuneData40

The memory phase of the CD4 T-cell response to influenza virus infection maintains its diverse antigen specificity.

流感病毒免疫记忆

CD4T细胞抗原特异性

T cell response was measured in CD4+ T cells, after 8-10 days, 30 days or 60 days post-infection.

ImmuneData30