CRYSTAL STRUCTURE OF HUMAN CHYMASE IN COMPLEX WITH COMPOUND47
收藏Protein Data Bank Japan2025-04-09 更新2026-04-19 收录
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CRYSTAL STRUCTURE OF HUMAN CHYMASE IN COMPLEX WITH COMPOUND47 Descriptor: 1-(1,3-dimethyl-2-oxidanylidene-benzimidazol-5-yl)-3-[[2-methyl-3-(trifluoromethyl)phenyl]methyl]-2,4-bis(oxidanylidene)pyrimidine-5-carboxylic acid, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Chymase, ... Authors: Schaefer, M, Fuerstner, C. Deposit date: 2024-08-01 Release date: 2024-11-27 Last modified: 2025-04-09 Method: X-RAY DIFFRACTION (1.793 Å) Cite: Discovery and Preclinical Characterization of Fulacimstat (BAY 1142524), a Potent and Selective Chymase Inhibitor As a New Profibrinolytic Approach for Safe Thrombus Resolution. J.Med.Chem., 68, 2025
创建时间：
2024-08-01
