Association of QRS/QT interval associated SNPs with SCD.

Chr, chromosome; OR, odds ratio; CI, confidence interval. Results are drawn from the SCD GWAS only (n = 1283 case, >20,000 controls). Trait beta estimates (β) are in milliseconds (ms). P-values are for a two-tailed test. Concordant Effect refers to whether the QRS/QT prolonging allele is associated with increased risk of SCD. Bold indicates significant after Bonferroni correction for the 49 SNPs tested. QRS results are drawn from [14] and QT results are drawn from the QTSCD study [13]. § These SNP represent the same genetic effect (r2 = 0.91).