To compare insulin-induced cells and non-insulin cells, YY1 knockdown and non-knockdown, the results showed that the mRNA and protein expression levels of IRS1, AKT1 and AKT3 were significantly increa

NIAID Data Ecosystem70

Transcriptome of insulin signalling associated transcription factor targets

胰岛素信号通路

转录组学分析

We report the transcritional targets of transcription factor downstream of insulin signalling. We knocked down transcription factors under reduced insulin signalling in Caenorhabditis elegans and did

NIAID Data Ecosystem30

Identification of Novel miR-21 Target Proteins in Multiple Myeloma Cells by Quantitative Proteomics

肿瘤蛋白质组学

microRNA靶标

Substantial evidence indicates that microRNA-21 (miR-21) is a key oncomiR in carcinogenesis and is significantly elevated in multiple myeloma (MM). In this study, we explored the role of miR-21 in hum

NIAID Data Ecosystem70

Table1_Ceramide metabolism associated with chronic dietary nutrient surplus and diminished insulin sensitivity in the liver, muscle, and adipose tissue of cattle.XLSX

动物营养代谢病

胰岛素信号通路

High dietary energy and protein supply is common practice in livestock nutrition, aiming to maximize growth and production performance. However, a chronic nutritional surplus induces obesity, promotes

NIAID Data Ecosystem40

Additional file 3 of Multi-omics profiling reveals microRNA-mediated insulin signaling networks

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