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STRUCTURE OF THE URACIL PHOSPHORIBOSYLTRANSFERASE, MUTANT C128V BOUND TO THE DRUG 5-FLUOROURACIL

NIAID Data Ecosystem2026-05-01 收录

蛋白-药物复合物结构解析

抗癌药物靶点研究

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STRUCTURE OF THE URACIL PHOSPHORIBOSYLTRANSFERASE, MUTANT C128V BOUND TO THE DRUG 5-FLUOROURACIL

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创建时间：

2024-02-14

蛋白-药物复合物结构解析

PARP抑制剂选择性机制

Structure of the catalytic domain of tankyrase 1 in complex with olaparib Descriptor: 4-(3-{[4-(cyclopropylcarbonyl)piperazin-1-yl]carbonyl}-4-fluorobenzyl)phthalazin-1(2H)-one, Poly [ADP-ribose] poly

Protein Data Bank Japan2023-10-18 更新70

Structure and Stability of Human Telomeric G-Quadruplex with Preclinical 9-Amino Acridines

抗癌药物靶点研究

G-四链体结构

G-quadruplexes are higher-order DNA structures formed from guanine-rich sequences, and have been identified as attractive anticancer drug targets. Elucidating the three-dimensional structure of G-quad

NIAID Data Ecosystem60

Bisphosphonate Inhibitors of Mammalian Glycolytic Aldolase

醛缩酶抑制剂

抗癌药物靶点研究

The glycolytic enzyme aldolase is an emerging drug target in diseases such as cancer and protozoan infections which are dependent on a hyperglycolytic phenotype to synthesize adenosine 5′-triphosphate

NIAID Data Ecosystem40

Room-temperature X-ray structure of SARS-CoV-2 main protease catalytic domain (residues 1-199-6H) in complex with ensitrelvir (ESV)

蛋白-药物复合物结构解析

抗新冠病毒药物设计

Room-temperature X-ray structure of SARS-CoV-2 main protease catalytic domain (residues 1-199-6H) in complex with ensitrelvir (ESV)

NIAID Data Ecosystem60

AKR1C2 complex with flurbiprofen

蛋白-药物复合物结构解析

非甾体抗炎药选择性机制

AKR1C2 complex with flurbiprofen Descriptor: 1,2-ETHANEDIOL, Aldo-keto reductase family 1 member C2, FLURBIPROFEN, ... Authors: Yosaatmadja, Y, Flanagan, J.U, Squire, C.J. Deposit date: 2013-03-24 Rel

Protein Data Bank Japan2023-09-20 更新50

STRUCTURE OF THE URACIL PHOSPHORIBOSYLTRANSFERASE, MUTANT C128V BOUND TO THE DRUG 5-FLUOROURACIL

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