Table S1 - <em>TrpA1</em> Regulates Thermal Nociception in <em>Drosophila</em>

Ca2+ signalling involved in thermal nociception responses. Ca2+ signaling components (elav-Gal4>UAS-IR fly lines) that exhibit defects in thermal nociception are listed from the strongest to weakest phenotype for noxious heat avoidance. An avoidance Z-score +/− SEM and repetitions are included. Lethality was scored for each cross (0 = lethal, 0.5 = semi-lethal, 1 = viable). A mean score of ≤0.6666 was considered lethal. A qualitative coordination score (0 = uncoordinated, 1 = coordinated) +/− SEM and number of repetitions are indicated for the re-screened lines. The CG numbers according to flybase annotation version 4.3 (FB4.3) and flybase annotation 5.7 (FB5.7) are included, as is the S19 score for RNAi off targeting effects (OTEs) and number of can repeats. A p-value is also included. Drosophila gene symbols and predicted human and mouse orthologs are shown.
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