CRYSTAL STRUCTURE OF LYSYL-TRNA SYNTHETASE FROM Mycobacterium tuberculosis COMPLEXED WITH L-LYSINE AND INHIBITOR DDD018870911

CRYSTAL STRUCTURE OF LYSYL-TRNA SYNTHETASE FROM Mycobacterium tuberculosis COMPLEXED WITH L-LYSINE AND INHIBITOR DDD018870911 Descriptor: 2-azanyl-6-[(1~{S})-2,2-bis(fluoranyl)cyclohexyl]-4-methoxy-7~{H}-pyrrolo[3,4-d]pyrimidin-5-one, LYSINE, Lysine--tRNA ligase 1 Authors: Dawson, A, Cleghorn, L.A.T, Davis, S.H. Deposit date: 2025-03-06 Release date: 2025-08-13 Last modified: 2025-08-27 Method: X-RAY DIFFRACTION (2.597 Å) Cite: Design and Development of Lysyl tRNA Synthetase Inhibitors, for the Treatment of Tuberculosis. J.Med.Chem., 68, 2025