BackgroundIn the fungal pathogen Candida albicans, amino acid substitutions of 14alpha-demethylase (CaErg11p, CaCYP51) are associated with azole antifungals resistance. This is an area of research whi
In the human fungal pathogen Candida albicans, a clinical isolate exhibited heritable and reversible drug resistance phenotype that is reminiscent of para-resistance. The goal of this study is to exam
Aspergillus fumigatus is the leading cause of pulmonary fungal diseases. Azoles have been used for many years as the main antifungal agents to treat and prevent invasive aspergillosis. However,
aCla, clarithromycin; Cli, clindamycin; Ery, erythromycin; Gm, gentamicin; Spc, spectinomycin; Str, streptomycin.bND, not done; DD503 is streptomycin resistant because of a chromosomal rpsL mutation.c