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Molecular mechanisms underlying reprogramming of mouse fibroblasts into pluripotent stem cells

ChEBI2010-06-08 更新2026-07-21 收录

细胞重编程

干细胞分子机制

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https://www.ebi.ac.uk/biostudies/ArrayExpress/studies/E-GEOD-21067 数据链接链接失效反馈

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Molecular mechanisms underlying reprogramming of mouse fibroblasts into pluripotent stem cells

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创建时间：

2010-06-08

细胞重编程

R-loop调控

R-loop induces genome instability and regulates gene expression. However, regulatory mechanism of R-loop in stem cell biology remains unclear. Here, we mapped the profiling of R-loops during reprogram

干细胞与再生医学数据中心2022-02-20 更新80

C2C12 murine myoblast cell line and 48 h 10 uM BIO treated C2C12 cellulate. Mus musculus

细胞重编程

心肌细胞去分化机制

In urodele amphibians, limb regeneration involves the dedifferentiation of muscle myotubes into single cells that may acquire pluripotent potential. We have employed small molecules (myoseverin and BI

NIAID Data Ecosystem50

Reprogramming to pluripotency is an ancient trait of vertebrate Oct4 and Pou2 proteins

细胞重编程

多能性基因功能保守性

The evolutionary origins of the gene network underlying cellular pluripotency, a central theme in developmental biology, have yet to be elucidated. In mammals, Oct4 is a factor crucial in the reprogra

NIAID Data Ecosystem40

Employing totipotent cells to reconstruct embryogenesis. Employing totipotent cells to reconstruct embryogenesis

细胞重编程

胚胎发育模型

This SuperSeries is composed of the SubSeries listed below. Overall design: Refer to individual Series

NIAID Data Ecosystem50

Comparison of hiPSCs, hESCs and fibroblasts

细胞重编程

基因表达谱比较分析

In our study, PRDM14 and NFRkB were found to enhance the reprogramming of human fibroblasts to hiPSCs in the presence of OCT4, SOX2, KLF4, with/without c-MYC (OSK/OSKC). To examnie if the obtained hiP

NIAID Data Ecosystem50

Molecular mechanisms underlying reprogramming of mouse fibroblasts into pluripotent stem cells

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