We investigated the specificity profiles of a variety of RNA guided adenosine deaminases while exploring roles of NLS/NES and hyperactive mutants via analysis of the transcriptome-wide off-target A->G
The predicted binding affinities are grouped with different symbols: * represents strong binding affinity (NDS NDS>−2.0), and others represent less likely binding due to
The important organs (heart, liver, spleen, lungs, kidneys) of mice 30 days after receiving a 30 μg plasmid/mouse dose of ARCHER treatment, were performed PCR for GPX4 and 3 potential off-target sites
