genome sequence of synthetic onoclytic HSV-1
收藏DataCite Commons2025-11-06 更新2026-05-05 收录
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In the present research, we applied an HSV-1 synthetic genomics platform to construct two oncolytic viruses, oHSV-1.1 and oHSV-1.2. oHSV-1.1 had the virulence gene ICP34.5 and ICP47 deleted for attenuation, and oHSV-1.2 was additionally armed with murine granulocyte macrophage-colony stimulating factor (GM-CSF) and interleukin-12 (IL-12). Here we present the genome sequencing data of oHSV-1.1 and oHSV-1.2
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创建时间：
2025-11-06
