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Structure of Mcl-1 in complex with compound 10d

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Protein Data Bank Japan2024-01-24 更新2026-03-21 收录
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Structure of Mcl-1 in complex with compound 10d Descriptor: (2~{R})-2-[5-(3-chloranyl-2-methyl-4-oxidanyl-phenyl)-6-ethyl-thieno[2,3-d]pyrimidin-4-yl]oxy-3-phenyl-propanoic acid, Induced myeloid leukemia cell differentiation protein Mcl-1 Authors: Dokurno, P, Szlavik, Z, Ondi, L, Csekei, M, Paczal, A, Szabo, Z.B, Radics, G, Murray, J, Davidson, J, Chen, I, Davis, B, Hubbard, R.E, Pedder, C, Surgenor, A.E, Smith, J, Robertson, A, LeToumelin-Braizat, G, Cauquil, N, Zarka, M, Demarles, D, Perron-Sierra, F, Geneste, O, Kotschy, A. Deposit date: 2019-03-11 Release date: 2019-08-07 Last modified: 2024-01-24 Method: X-RAY DIFFRACTION (2.15 Å) Cite: Structure-Guided Discovery of a Selective Mcl-1 Inhibitor with Cellular Activity. J.Med.Chem., 62, 2019
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2019-03-11
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