In the rapidly advancing field of synthetic biology, there exists a critical need for technology to discover targeting moieties for therapeutic biologics. We are developing developed INSPIRE-seq, an a

NIAID Data Ecosystem20

Evaluating LC–MS/MS To Measure Accumulation of Compounds within Bacteria

抗菌药物发现

细菌内化合物积累分析

A general method for determining bacterial uptake of compounds independent of antibacterial activity would be a valuable tool in antibacterial drug discovery. LC-MS/MS assays have been described, but

NIAID Data Ecosystem40

Crystal structure of S. aureus FabI inhibited by SKTS1

抑制剂结构

抗菌药物发现

Crystal structure of S. aureus FabI inhibited by SKTS1 Descriptor: 6-[4-(4-hexyl-2-oxidanyl-phenoxy)phenoxy]pyridin-2-ol, Enoyl-[acyl-carrier-protein] reductase [NADPH], NADP NICOTINAMIDE-ADENINE-DINU

Protein Data Bank Japan2024-01-24 更新30

SLAY nanobody screening

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