Bicarbonate signalling via GPCR regulates ischaemia-reperfusion injury

Figshare2024-02-28 更新2026-04-28 收录

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https://figshare.com/articles/dataset/Bicarbonate_signalling_via_GPCR_regulates_ischaemia-reperfusion_injury/24431842 数据链接链接失效反馈

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This is the source data for the manuscript "Bicarbonate signalling via GPCR regulates ischaemia-reperfusion injury".

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2024-02-28

Protective role of silent information regulator 1 against hepatic ischemia: effects on oxidative stress injury, inflammatory response, and MAPKs

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氧化应激与炎症

Objective : Previous studies have verified that silent information regulator 1 (SIRT1), a class III histone deacetylase, protects against ischemia reperfusion (IR) injury (IRI) in some organs. I

DataCite Commons2024-03-24 更新120

Downregulation of autophagy is associated with severe ischemia-reperfusion-induced acute kidney injury in overexpressing C-reactive protein mice

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自噬调节机制

C-reactive protein (CRP), was recently reported to be closely associated with poor renal function in patients with acute kidney injury (AKI), but whether CRP is pathogenic or a mere biomarker in AKI r

NIAID Data Ecosystem40

Additional file 5 of Transcriptomic exploration combined with experimental validation: uncovering the potential value of biomarkers related to ammonia-induced cell death in hepatic ischemia–reperfusion injury

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生物标志物研究

Additional file 5. Information on 586 DEGs

NIAID Data Ecosystem20

Data_Sheet_1_Human Recombinant Alkaline Phosphatase (Ilofotase Alfa) Protects Against Kidney Ischemia-Reperfusion Injury in Mice and Rats Through Adenosine Receptors.PDF

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药物干预机制

Adenosine triphosphate (ATP) released from injured or dying cells is a potent pro-inflammatory “danger” signal. Alkaline phosphatase (AP), an endogenous enzyme that de-phosphorylates extracellular ATP

NIAID Data Ecosystem40

Assessment of kidney biopsies and quantification of inflammatory infiltrate in rat control and ischemia/reperfusion groups at different times.

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T3实验性治疗

Values are expressed as mean ± standard deviation. Control: Placebo-treated (SO-P) + sham-operated T3- treated (SO- T3); I/R-injured placebo-treated (IR-P); I/R-injured T3-treated (IR- T3) groups. * P

NIAID Data Ecosystem30

Bicarbonate signalling via GPCR regulates ischaemia-reperfusion injury

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