Supplementary Figure 4. gH mAbs are specific for HCMV neutralization. Neutralization of HSV-1 US-11 GFP (MOI 0.01) using anti-gH mAbs (50-0.016 ug/mL) and assessed usingGFP as a readout for infection
Sera collected at different time points before and after challenge were tested against single-round competent virus bearing an Env protein of the SHIVsf162p4 virus inoculum. The reciprocal of serum di
1days post onset of symptoms. 2Last positive titer in 90% Focus-reduction micro-neutralization (FRμNT) assay. 3Calculated actual 90% neutralization titers based on a nonlinear regression of the FRμNT
#Neutralization epitope in the Gp120 outer domain before CD4 binding.$Neutralization epitope induced in Gp120 after CD4 binding.*Epitopes outside of the CD4 binding site [37].@The effect of each antib
