DNA methylation-based classification of common renal tumors

In present work one of our main objectives was to collect enough DNA methylation profiles of diverse tumor types in renal cancer. So, we used a collection of newly processed samples on DNA methylation data to have a variety of diverse kidney tumors from various sources. We processed a subset of samples (n=156) profiled as a part of our routine clinical methylation testing for kidney cancer at NIH. We collected one subset of samples (n =173) from our collaborators at UCSF and another subset of samples (n=82) from NYU. All samples were profiled in accordance with standard manufacturer’s protocol for Illumina EPIC array (http://www.illumina.com/).