We address the question of the nature of the signal perceived by iNKT cells promoting their specification, we analyzed iNKT cell development in relevant TCR Vα14-Jα18 alpha chain transgenic mice (Vα14
To demonstrate aMT-exo could induce multi-antigenic response, PBS and aMT-exos were subcutaneously injected into mice. Then CD8 T cells were sorted out from lymph nodes and used for T cell receptor be